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Effect of sex differences on the emergence of ctDNA RAS mutations in RAS wild-type colorectal cancer

Abstract In some cases of RAS wild-type metastatic colorectal cancer (mCRC), mutant RAS may emerge during chemotherapy. This study aimed to identify the clinicopathological factors associated with the emergence of RAS mutations during treatment. This single-center retrospective study included 43 pat...

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Autori principali: Kenta Iguchi, Mamoru Uchiyama, Masahiro Asari, Koji Numata, Manabu Shiozawa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2026-03-01
Serie:Scientific Reports
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Accesso online:https://doi.org/10.1038/s41598-026-42920-2
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