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Microglial heterogeneity: influence of human 2D, 3D, and co-culture models on gene expression and immune function

Microglia, the resident immune cells of the central nervous system, exhibit substantial phenotypic and functional diversity shaped by local microenvironmental cues. While advanced in vitro human microglial models exist, the influence of culture dimensionality and cellular context on microglial state...

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Bibliografski detalji
Glavni autori: Fazeleh Etebar, Anthony R. White, Hazel Quek
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2026-02-01
Serija:Frontiers in Cellular Neuroscience
Teme:
Online pristup:https://www.frontiersin.org/articles/10.3389/fncel.2026.1770518/full
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