The Host NADase CD38 Promotes JEV Replication by Targeting the NAD+/SIRT1 Axis
The manipulation of host cellular metabolism is a key strategy for flaviviruses like Japanese encephalitis virus (JEV) to establish a productive infection. This study identifies the host NADase CD38 as a central regulator of this process. Using a CRISPR/Cas9-generated CD38 knockout (KO) TM3 cell mod...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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MDPI AG
2026-04-01
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| Schriftenreihe: | Microorganisms |
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| Online-Zugang: | https://www.mdpi.com/2076-2607/14/4/796 |
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