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Neuromyotonia and CASPR2 Antibodies: Electrophysiological Clues to Disease Pathophysiology

Contactin-associated protein-like 2 (CASPR2) is a transmembrane protein of the neurexin superfamily, essential for clustering voltage-gated potassium channels, particularly Kv1, at the juxtaparanodal regions of myelinated axons. This precise localisation is essential for maintaining normal axonal ex...

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Bibliografische Detailangaben
Hauptverfasser: João Moura, Pietro Antenucci, Ester Coutinho, Kailash P. Bhatia, Lorenzo Rocchi, Anna Latorre
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2025-09-01
Schriftenreihe:Biomolecules
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Online-Zugang:https://www.mdpi.com/2218-273X/15/9/1262
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