Neuromyotonia and CASPR2 Antibodies: Electrophysiological Clues to Disease Pathophysiology

Contactin-associated protein-like 2 (CASPR2) is a transmembrane protein of the neurexin superfamily, essential for clustering voltage-gated potassium channels, particularly Kv1, at the juxtaparanodal regions of myelinated axons. This precise localisation is essential for maintaining normal axonal ex...

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Autors principals:	João Moura, Pietro Antenucci, Ester Coutinho, Kailash P. Bhatia, Lorenzo Rocchi, Anna Latorre
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2025-09-01
Col·lecció:	Biomolecules
Matèries:	CASPR2 peripheral nerve hyperexcitability neuromyotonia afterdischarges clinical neurophysiology
Accés en línia:	https://www.mdpi.com/2218-273X/15/9/1262
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