Conditional immortalization of mesenchymal stem cells and their extracellular vesicles therapy for interstitial cystitis/bladder pain syndrome

Abstract Background Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic condition characterized by debilitating pelvic pain. Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) are recognized as pivotal mediators of MSCs’ paracrine activity and represent a novel therapeutic...

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Hauptverfasser:	Guolong Liao, Canling Long, Rui Guo, Sushan Wang, Ruijuan Han, Jianhua Yang, Jia Liu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-08-01
Schriftenreihe:	Stem Cell Research & Therapy
Schlagworte:	MSCs Conditional immortalization EVs IC/BPS Anti-inflammatory
Online-Zugang:	https://doi.org/10.1186/s13287-025-04615-9
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