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Conditional immortalization of mesenchymal stem cells and their extracellular vesicles therapy for interstitial cystitis/bladder pain syndrome

Abstract Background Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic condition characterized by debilitating pelvic pain. Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) are recognized as pivotal mediators of MSCs’ paracrine activity and represent a novel therapeutic...

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Principais autores: Guolong Liao, Canling Long, Rui Guo, Sushan Wang, Ruijuan Han, Jianhua Yang, Jia Liu
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2025-08-01
Series:Stem Cell Research & Therapy
Assuntos:
MSCs
Conditional immortalization
EVs
IC/BPS
Anti-inflammatory
Acceso en liña:https://doi.org/10.1186/s13287-025-04615-9
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