Carbothioamides as anticancer agents: synthesis, in-vitro activity, structure-activity relationship evaluations and molecular docking

Carbothioamides exhibit many biological properties, including antiviral, antibacterial and anticancer activities. Their ability to interfere with DNA synthesis is mainly responsible for their anticancer activities. Here, twelve phenyl-substituted carbothioamides (2−13) were synthesized and character...

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Detalhes bibliográficos

Principais autores:	Basharat Ali, Muhammad Riaz, Ajmal Khan, Nadir Rasheed, Muhammad Masood, Ali Iftikhar, Amir Faisal, Sobia Ahsan Halim, Jalal Uddin, Afnan Jan, Ahmed Al-Harrasi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-09-01
coleção:	Results in Chemistry
Assuntos:	Synthesis Thiosemicarbazides Carbothioamides Anticancer activities Molecular docking ADMET prediction
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211715625005995
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