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Comparison of efficacy of exosomes derived from human umbilical cord blood mesenchymal stem cells in treating mouse acute lung injury via different routes

ObjectiveTo investigate the therapeutic efficacy of human umbilical cord blood mesenchymal stem cell-derived exosomes (hUCMSC-Exo) in a lipopolysaccharide (LPS)-induced acute lung injury (ALI) mouse model and compare the effects of different administration routes.MethodsAn ALI mouse model was establ...

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Principais autores: Jing Chen, Shuang Liu, Jizhen Zou, Yi Wang, Haiyan Ge, Yi Hui, Siyuan Huang, Wei Li, Weilan Na, Xiaolan Huang, Lin Bai, Yiying Huang, Dong Qu
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-05-01
Serier:Frontiers in Pediatrics
Fag:
acute lung injury
acute respiratory distress syndrome
mesenchymal stem cells
exosomes
cytokines
Online adgang:https://www.frontiersin.org/articles/10.3389/fped.2025.1560915/full
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