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Overexpression of miRNA-216 in exosomes derived from umbilical cord mesenchymal stem cells promotes angiogenesis and improves functional recovery after spinal cord injury

Objective(s): This study aimed to engineer miR-216-overexpressing umbilical cord mesenchymal stem cells (UCMSCs) to generate miR-216-enriched UCMSC-derived exosomes (UCMSC-Exos) and evaluate their therapeutic potential in Spinal cord injury (SCI).Materials and Methods: miR-216 overexpression was ach...

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Bibliografiske detaljer
Principais autores: Hengde Li, Renfeng Yi, Youbing Fan, Gonghao Zhan, Taoyuan Xiao
Format: Artigo
Sprog:Inglês
Udgivet: Mashhad University of Medical Sciences 2025-10-01
Serier:Iranian Journal of Basic Medical Sciences
Fag:
Online adgang:https://ijbms.mums.ac.ir/article_26182_5cfaf562e1d0f81826d7073a626aa3e4.pdf
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