Plasma‐based analysis of ERBB2 mutational status by multiplex digital PCR in a large series of patients with metastatic breast cancer

Erb‐b2 receptor tyrosine kinase 2 (ERBB2)‐activating mutations are therapeutically actionable alterations found in various cancers, including metastatic breast cancer (MBC). We developed multiplex digital PCR assays to detect and quantify ERBB2 mutations in circulating tumor DNA from liquid biopsies...

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Principais autores:	Julien Corné, Véronique Quillien, Florence Godey, Mathilde Cherel, Agathe Cochet, Fanny Le Du, Lucie Robert, Héloïse Bourien, Angélique Brunot, Laurence Crouzet, Christophe Perrin, Claudia Lefeuvre‐Plesse, Véronique Diéras, Thibault De la Motte Rouge
Formato:	Artigo
Idioma:	Inglês
Publicado:	Wiley 2024-11-01
Series:	Molecular Oncology
Assuntos:	circulating tumor DNA ERBB2 liquid biopsies metastatic breast cancer multiplex digital PCR plasma
Acceso en liña:	https://doi.org/10.1002/1878-0261.13592
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