Plasma‐based analysis of ERBB2 mutational status by multiplex digital PCR in a large series of patients with metastatic breast cancer

Erb‐b2 receptor tyrosine kinase 2 (ERBB2)‐activating mutations are therapeutically actionable alterations found in various cancers, including metastatic breast cancer (MBC). We developed multiplex digital PCR assays to detect and quantify ERBB2 mutations in circulating tumor DNA from liquid biopsies...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Julien Corné, Véronique Quillien, Florence Godey, Mathilde Cherel, Agathe Cochet, Fanny Le Du, Lucie Robert, Héloïse Bourien, Angélique Brunot, Laurence Crouzet, Christophe Perrin, Claudia Lefeuvre‐Plesse, Véronique Diéras, Thibault De la Motte Rouge
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2024-11-01
Schriftenreihe:	Molecular Oncology
Schlagworte:	circulating tumor DNA ERBB2 liquid biopsies metastatic breast cancer multiplex digital PCR plasma
Online-Zugang:	https://doi.org/10.1002/1878-0261.13592
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