Involvement of LncRNA FAF in chemotherapy-induced cardiotoxicity by mediating pyroptosis through modulation of the NLRP3-Caspase-1 signaling pathway

Abstract Purpose Chemotherapeutic agents, though highly effective in eliminating tumor cells, frequently cause varying degrees of myocardial injury. Doxorubicin (DOX) is a leading extensively used anthracycline-based chemotherapy agents. The present research sought to explore the role of lncRNA FAF...

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Principais autores:	Ziyu Feng, Jinhui Sun, Qiang Geng, Bichen He, Jingjing Zhang, Yiheshan Ainiwaer, Bing Zhang, Yuanming Zhang
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2025-12-01
Serija:	Scientific Reports
Teme:	LncRNA FAF Cardiomyocyte NLRP3-Caspase-1 axis Cellular pyroptosis DOX
Online dostop:	https://doi.org/10.1038/s41598-025-31983-2
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