Development of inhibitory antibodies to therapeutic factor VIII in severe hemophilia A is associated with microsatellite polymorphisms in the HMOX1 promoter

Induction of heme oxygenase-1, a stress-inducible enzyme with anti-inflammatory activity, reduces the immunogenicity of therapeutic factor VIII in experimental hemophilia A. In humans, heme oxygenase-1 expression is modulated by polymorphisms in the promoter of the heme oxygenase-1-encoding gene (HM...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Yohann Repessé, Ivan Peyron, Jordan D Dimitrov, Suryasarathi Dasgupta, Elika Farrokhi Moshai, Catherine Costa, Annie Borel-Derlon, Benoit Guillet, Roseline D’Oiron, Achille Aouba, Chantal Rothschild, Johannes Oldenburg, Anna Pavlova, Srinivas V Kaveri, Sébastien Lacroix-Desmazes
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Ferrata Storti Foundation 2013-10-01
Sarja:	Haematologica
Linkit:	https://haematologica.org/article/view/6818
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