Factor VIII bypasses CD91/LRP for endocytosis by dendritic cells leading to T-cell activation
Background The development of factor VIII (FVIII) inhibitors remains the major hurdle in the clinical management of patients with hemophilia A. FVIII uptake by professional antigen-presenting cells (APC) is the first step involved in initiation of immune responses to FVIII. Studies on FVIII cataboli...
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| Principais autores: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ferrata Storti Foundation
2008-01-01
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| coleção: | Haematologica |
| Acesso em linha: | https://haematologica.org/article/view/4721 |
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