Factor VIII bypasses CD91/LRP for endocytosis by dendritic cells leading to T-cell activation

Background The development of factor VIII (FVIII) inhibitors remains the major hurdle in the clinical management of patients with hemophilia A. FVIII uptake by professional antigen-presenting cells (APC) is the first step involved in initiation of immune responses to FVIII. Studies on FVIII cataboli...

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Библиографические подробности

Главные авторы:	Suryasarathi Dasgupta, Ana Maria Navarrete, Sebastien André, Bharath Wootla, Sandrine Delignat, Yohann Repessé, Jagadeesh Bayry, Antonino Nicoletti, Evgueni L. Saenko, Roseline d’Oiron, Marc Jacquemin, Jean-Marie Saint-Remy, Srini V. Kaveri, Sebastien Lacroix-Desmazes
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Ferrata Storti Foundation 2008-01-01
Серии:	Haematologica
Online-ссылка:	https://haematologica.org/article/view/4721
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