Development of potent Affitin-based bispecific NK cell engagers for the therapy of MSLN-expressing cancers

Well-characterized tumor-associated antigens (TAAs) represent targets of interest in many anticancer therapeutic strategies. Although the use of monoclonal antibodies has led this field for years, the development of smaller molecules, with improved properties, holds great potential for specific anti...

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Autors principals:	Tina Briolay, Tacien Petithomme, Hermelyne Gravoueille, Judith Fresquet, Sylvia Lambot, Pauline Cossard, Barbara Mouratou, Agnès Fortun, Karine Bernardeau, Agnès Quéméner, Mike Maillasson, Nicolas Boisgerault, Erwan Mortier, François Davodeau, Frédéric Pecorari, Christophe Blanquart
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2025-12-01
Col·lecció:	Molecular Therapy: Oncology
Matèries:	MT: Regular Issue mesothelin targeting non-Ig scaffold Affitin bispecific NK engagers
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S295032992500164X
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