The Receptor Tyrosine Kinase TrkA Is Increased and Targetable in HER2-Positive Breast Cancer

The tyrosine kinase receptor A (NTRK1/TrkA) is increasingly regarded as a therapeutic target in oncology. In breast cancer, TrkA contributes to metastasis but the clinicopathological significance remains unclear. In this study, TrkA expression was assessed via immunohistochemistry of 158 invasive du...

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Библиографические подробности

Главные авторы:	Nathan Griffin, Mark Marsland, Severine Roselli, Christopher Oldmeadow, John Attia, Marjorie M. Walker, Hubert Hondermarck, Sam Faulkner
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2020-09-01
Серии:	Biomolecules
Предметы:	breast cancer tyrosine kinase receptor A (NTRK1/TrkA) human epidermal growth factor receptor 2 (HER2) clinical biomarker therapeutic target
Online-ссылка:	https://www.mdpi.com/2218-273X/10/9/1329
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