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The expression system affects the binding affinity between p75NTR and proNGF

ProNGF (nerve growth factor) is a precursor of NGF and a signaling peptide exerting opposite effects on neuronal cells, i.e., apoptotic or neuritogenic. The conflicting biological activity of proNGF depends on the relative levels of two membrane receptors, TrkA and p75NTR. The effect of proNGF depen...

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Principais autores: Mami Hino, Masayuki Nakanishi, Hiroshi Nomoto
格式: Artigo
語言:Inglês
出版: Elsevier 2024-07-01
叢編:Biochemistry and Biophysics Reports
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在線閱讀:http://www.sciencedirect.com/science/article/pii/S2405580824000669
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