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Distinct overlapping functions for Prickle1 and Prickle2 in the polarization of the airway epithelium

Planar cell polarity (PCP) signaling polarizes cells within the plane of an epithelium. In the airways, planar cell polarity signaling orients the directional beating of motile cilia required for effective mucociliary clearance. The planar cell polarity signaling mechanism is best understood from wo...

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Detalles Bibliográficos
Principais autores: Koshi Kunimoto, Alexis T. Weiner, Jeffrey D. Axelrod, Eszter K. Vladar
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cell and Developmental Biology
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fcell.2022.976182/full
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