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Efficacy of Combined Rifampicin Formulations Delivered by the Pulmonary Route to Treat Tuberculosis in the Guinea Pig Model

Liposomes, as vehicles alone or in combination with rifampicin (RIF) microparticles (RMs), were evaluated as vehicles to enhance the permeation of RIF into granulomas. RIF liposomes (RLs) were extruded through a 0.1 µm polypropylene membrane. RMs were prepared by the solvent evaporation method. Four...

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Hlavní autoři: Lucila Garcia-Contreras, Vasu Sethuraman, Masha Kazantseva, Anthony Hickey
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2021-08-01
Edice:Pharmaceutics
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On-line přístup:https://www.mdpi.com/1999-4923/13/8/1309
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