QR-Code

Early motor deficits, sleep dysfunction and reduction in dopaminergic neurons in a PARK7-/- zebrafish larval model of Parkinson’s disease

Abstract Parkinson’s Disease (PD) is the fastest-growing neurological disorder and only symptomatic treatment is available. Zebrafish are ideally suited for high-throughput screening of disease modifying drugs and mechanistic studies. Mutations in PARK7 are associated with early onset familial PD, h...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Nora Solheim, Brígida R. Pinho, Nuno A. S. Oliveira, Leonor P. Lima, Aina Børve, Jorge M. A. Oliveira, Kari E. Fladmark
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2026-02-01
Schriftenreihe:Scientific Reports
Schlagworte:
Parkinson’s disease
Zebrafish model
Sleep
Motor
Non-motor
Prodromal
Online-Zugang:https://doi.org/10.1038/s41598-026-39692-0
Tags: Tag hinzufügen
Keine Tags, Fügen Sie das erste Tag hinzu!

Ähnliche Einträge