In Vitro Activity of Geldanamycin Derivatives against Schistosoma japonicum and Brugia malayi
Geldanamycin (GA) is a benzoquinone-containing ansamycin that inhibits heat shock protein 90. GA derivatives are being evaluated as anti-neoplastic agents, but their utility against parasites whose heat shock proteins (Hsps) have homology with human Hsp90 is unknown. The activities of four syntheti...
Na minha lista:
| Principais autores: | , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Wiley
2010-01-01
|
| Serier: | Journal of Parasitology Research |
| Online adgang: | http://dx.doi.org/10.1155/2010/716498 |
| Tags: |
Ingen Tags, Vær først til at tagge denne postø!
|