Design, Synthesis and Cytotoxicity Study of Primary Amides as Histone Deacetylase Inhibitors

Primary amide derivatives as histone deacetylase inhibitors (HDACIs) are very rare. This paper describes the synthesis of primary amide derivatives (compounds 6 and 7) that have the requirements to be histone deacetylase inhibitors of the zinc-binding type. Both of them exhibited good cytotoxicity a...

תיאור מלא

מידע ביבליוגרפי

Principais autores:	Duraid Al-Amily, Mohammed H. Mohammed
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	College of Pharmacy University of Baghdad 2019-12-01
סדרה:	Iraqi Journal of Pharmaceutical Sciences
נושאים:	primary amides, hdacis, adipic monoanilide amide, pimelic monoanilide amide
גישה מקוונת:	http://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/933
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!