Enhanced amphiregulin exposure promotes modulation of the high grade serous ovarian cancer tumor immune microenvironment

High grade serous ovarian cancer (HGSOC) is a lethal gynecologic malignancy in which chemoresistant recurrence rates remain high. Furthermore, HGSOC patients have demonstrated overall low response rates to clinically available immunotherapies. Amphiregulin (AREG), a low affinity epidermal growth fac...

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Autors principals:	Jasmine Ebott, Julia McAdams, Chloe Kim, Corrine Jansen, Morgan Woodman, Payton De La Cruz, Christoph Schrol, Jennifer Ribeiro, Nicole James
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2024-05-01
Col·lecció:	Frontiers in Pharmacology
Matèries:	amphiregulin (AREG) high-grade serous ovarian cancer tumor immune microenvioronment immunosupperssion chemoresistance
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1375421/full
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