Modulation of the tumor microenvironment by the ubiquitin–proteasome system in colorectal cancer

Abstract Background Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide, with the tumor microenvironment (TME) playing a pivotal role in its progression and therapeutic resistance. The ubiquitin–proteasome system (UPS), a central regulator of intracellular protein degrad...

Descripción completa

Detalles Bibliográficos

Autores principales:	Xuan Wang, Yi Ren, Ruihao Song, Jia Liu, Yaojun Zhou, Sihai Yang, Yadong Liu, Yi Lei, Xin Zhao
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2025-12-01
Colección:	Journal of Translational Medicine
Materias:	Colorectal cancer Tumor microenvironment Ubiquitin–proteasome system Immune escape Targeted therapy Protein degradation
Acceso en línea:	https://doi.org/10.1186/s12967-025-07487-y
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!