Modulation of the tumor microenvironment by the ubiquitin–proteasome system in colorectal cancer

Abstract Background Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide, with the tumor microenvironment (TME) playing a pivotal role in its progression and therapeutic resistance. The ubiquitin–proteasome system (UPS), a central regulator of intracellular protein degrad...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Xuan Wang, Yi Ren, Ruihao Song, Jia Liu, Yaojun Zhou, Sihai Yang, Yadong Liu, Yi Lei, Xin Zhao
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2025-12-01
Serie:	Journal of Translational Medicine
Soggetti:	Colorectal cancer Tumor microenvironment Ubiquitin–proteasome system Immune escape Targeted therapy Protein degradation
Accesso online:	https://doi.org/10.1186/s12967-025-07487-y
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!