Novel 4-alkoxy Meriolin Congeners Potently Induce Apoptosis in Leukemia and Lymphoma Cells

<i>Meriolins</i> (3-(pyrimidin-4-yl)-7-azaindoles) are synthetic hybrids of the naturally occurring alkaloids <i>variolin</i> and <i>meridianin</i> and display a strong cytotoxic potential. We have recently shown that the novel derivative <i>meriolin</i> <b>16</b> is highly cytotoxic in several lymp...

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Detalles Bibliográficos

Principais autores:	Karina S. Krings, Tobias R. Wassenberg, Pablo Cea-Medina, Laura Schmitt, Ilka Lechtenberg, Tanya R. Llewellyn, Nan Qin, Holger Gohlke, Sebastian Wesselborg, Thomas J. J. Müller
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2024-12-01
Series:	Molecules
Assuntos:	apoptosis inducers 7-azaindoles biheteroaryls cyclin dependent kinases (CDK) leukemia cell lines lymphoma cell lines
Acceso en liña:	https://www.mdpi.com/1420-3049/29/24/6050
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