ARPC5 isoforms and their regulation by calcium-calmodulin-N-WASP drive distinct Arp2/3-dependent actin remodeling events in CD4 T cells

CD4 T cell activation induces nuclear and cytoplasmic actin polymerization via the Arp2/3 complex to activate cytokine expression and strengthen T cell receptor (TCR) signaling. Actin polymerization dynamics and filament morphology differ between nucleus and cytoplasm. However, it is unclear how the...

תיאור מלא

מידע ביבליוגרפי

Principais autores:	Lopamudra Sadhu, Nikolaos Tsopoulidis, Md Hasanuzzaman, Vibor Laketa, Michael Way, Oliver T Fackler
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	eLife Sciences Publications Ltd 2023-05-01
סדרה:	eLife
נושאים:	nuclear F-actin Arp2/3 complex CD4 T cell activation DNA replication stress
גישה מקוונת:	https://elifesciences.org/articles/82450
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!