Synthesis, Screening and Characterization of Novel Potent Arp2/3 Inhibitory Compounds Analogous to CK-666

Branched actin networks polymerized by the Actin-related protein 2 and 3 (Arp2/3) complex play key roles in force generation and membrane remodeling. These networks are particularly important for cell migration, where they drive membrane protrusions of lamellipodia. Several Arp2/3 inhibitory compoun...

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מידע ביבליוגרפי

Principais autores:	Artem I. Fokin, Roman N. Chuprov-Netochin, Alexander S. Malyshev, Stéphane Romero, Marina N. Semenova, Leonid D. Konyushkin, Sergey V. Leonov, Victor V. Semenov, Alexis M. Gautreau
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2022-05-01
סדרה:	Frontiers in Pharmacology
נושאים:	Arp2/3 branched actin Arp2/3 inhibitors CK-666 actin polymerization
גישה מקוונת:	https://www.frontiersin.org/articles/10.3389/fphar.2022.896994/full
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!