Improving effects of melatonin on memory and synaptic potentiation in a mouse model of Alzheimer’s-like disease: the involvement of glutamate homeostasis and mGluRs receptors

Abstract Background Alzheimer's disease (AD) is characterized by progressive cognitive decline and synaptic dysfunction, largely driven by amyloid plaques and neurofibrillary tangles (NFTs) composed of hyperphosphorylated tau. These pathological hallmarks disrupt glutamate signaling, which is essent...

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Váldodahkkit:	Narjes Khatoun Shabani Sadr, Fatemeh Bakhtiarzadeh, Koorosh Shahpasand, Javad Mirnajafi-Zadeh, Mehrdad Behmanesh
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	BMC 2025-03-01
Ráidu:	Behavioral and Brain Functions
Fáttát:	Alzheimer's disease Memory Synaptic plasticity Glutamate signaling Melatonin Metabotropic glutamate receptors
Liŋkkat:	https://doi.org/10.1186/s12993-025-00271-4
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