Single-cell RNA sequencing reveals disease associated changes in brain endothelial cells in the 5XFAD mouse
Abstract Vascular dysfunction is a key contributor to Alzheimer’s disease (AD) pathology, where changes to the endothelium and its crucial role in maintaining blood-brain barrier (BBB) integrity have been of particular emphasis. The transgenic 5XFAD (5X Familial Alzheimer’s Disease) mouse model, whi...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BMC
2026-01-01
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| シリーズ: | Fluids and Barriers of the CNS |
| 主題: | |
| オンライン･アクセス: | https://doi.org/10.1186/s12987-026-00766-w |
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