Folate-mediated transgenerational inheritance of sperm DNA methylation patterns correlate with spinal axon regeneration

In mammals, the molecular mechanisms underlying transgenerational inheritance of phenotypic traits in serial generations of progeny after ancestral environmental exposures, without variation in DNA sequence, remain elusive. We’ve recently described transmission of a beneficial trait in rats and mice...

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Principais autores:	Andy Madrid, Joyce Koueik, Ligia A. Papale, Roy Chebel, Isabelle Renteria, Emily Cannon, Kirk J. Hogan, Reid S. Alisch, Bermans J. Iskandar
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2024-12-01
coleção:	Epigenetics
Assuntos:	Folic acid whole genome methylation sequencing (WGMS) CNS regeneration transgenerational epigenetic inheritance spinal cord injury
Acesso em linha:	https://www.tandfonline.com/doi/10.1080/15592294.2024.2380930
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