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Comprehensive mapping of 5-hydroxymethylcytosine epigenetic dynamics in axon regeneration

In contrast to central nervous system neurons, dorsal root ganglia (DRG) neurons can switch to a regenerative state after peripheral axotomy. In a screen for chromatin regulators of the regenerative responses in this conditioning lesion paradigm, we identified Tet methylcytosine dioxygenase 3 (Tet3)...

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Main Authors: Yong-Hwee Eddie Loh, Andrew Koemeter-Cox, Mattéa J. Finelli, Li Shen, Roland H. Friedel, Hongyan Zou
Format: Artigo
Language:Inglês
Published: Taylor & Francis Group 2017-02-01
Series:Epigenetics
Subjects:
5hmc
axon injury
axon regeneration
conditioning lesion
dna methylation
drg
epigenetics
regeneration-associated genes (rag)
tet
Online Access:http://dx.doi.org/10.1080/15592294.2016.1264560
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