Measuring growth, resistance, and recovery after artemisinin treatment of Plasmodium falciparum in a single semi-high-throughput assay

Abstract Background Artemisinin partial resistance (ART-R) has spread throughout Southeast Asia and mutations in Pfkelch13, the molecular marker of resistance, are widely reported in East Africa. Effective in vitro assays and robust phenotypes are crucial for monitoring populations for the emergence...

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Autors principals:	Mackenzie A. C. Sievert, Tarrick Qahash, Puspendra P. Singh, Douglas A. Shoue, Lisa A. Checkley, Katelyn Vendrely Brenneman, Zione Cassady, Sudhir Kumar, Xue Li, François H. Nosten, Timothy J. C. Anderson, Ashley M. Vaughan, Jeanne Romero-Severson, Michael T. Ferdig
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-08-01
Col·lecció:	Malaria Journal
Matèries:	Ring-stage survival assay Artemisinin resistance Plasmodium falciparum Kelch13 Phenotypes Genetic cross
Accés en línia:	https://doi.org/10.1186/s12936-025-05481-9
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