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Intrathecal injection of rituximab inhibits microglial M1 polarisation to alleviate neuropsychiatric SLE symptoms via the cAMP/PKA/CREB signalling pathway

Objective The objective of this study was to investigate the effects of rituximab (RTX) intrathecal injection on antibody levels in serum and cerebrospinal fluid (CSF), hippocampal tissue and neuronal injury and the behaviour of central neuropsychological lupus erythematosus (cNPSLE) model mice and...

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Váldodahkkit: Jing Zhao, Chunyan Li, Yong Chen, Wang Yu, AnMao Li, Yupei Lin, Xiao Li Pan, Mei Tian
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: BMJ Publishing Group 2026-02-01
Ráidu:Lupus Science and Medicine
Liŋkkat:https://lupus.bmj.com/content/13/1/e001774.full
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