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Intrathecal injection of rituximab inhibits microglial M1 polarisation to alleviate neuropsychiatric SLE symptoms via the cAMP/PKA/CREB signalling pathway

Objective The objective of this study was to investigate the effects of rituximab (RTX) intrathecal injection on antibody levels in serum and cerebrospinal fluid (CSF), hippocampal tissue and neuronal injury and the behaviour of central neuropsychological lupus erythematosus (cNPSLE) model mice and...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jing Zhao, Chunyan Li, Yong Chen, Wang Yu, AnMao Li, Yupei Lin, Xiao Li Pan, Mei Tian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMJ Publishing Group 2026-02-01
Cyfres:Lupus Science and Medicine
Mynediad Ar-lein:https://lupus.bmj.com/content/13/1/e001774.full
Tagiau: Ychwanegu Tag
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