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Evaluation and Selection of the Inhaler Device for Treprostinil Palmitil Inhalation Powder

Treprostinil palmitil (TP) is a prodrug of treprostinil that has been formulated as an inhaled powder, termed TPIP, for evaluation in patients with pulmonary arterial hypertension. In these characterization studies we investigated the aerosol performance of TPIP in response to changes in capsule fil...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Helena Gauani, Thomas Baker, Zhili Li, Vladimir S. Malinin, Walter Perkins, Eugene Sullivan, David Cipolla
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2022-04-01
Schriftenreihe:Frontiers in Drug Delivery
Schlagworte:
device performance
dry powder inhaler
drug delivery
aerosol characterization
treprostinil palmitil
fine particle dose
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fddev.2022.864922/full
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