Evaluation and Selection of the Inhaler Device for Treprostinil Palmitil Inhalation Powder

Treprostinil palmitil (TP) is a prodrug of treprostinil that has been formulated as an inhaled powder, termed TPIP, for evaluation in patients with pulmonary arterial hypertension. In these characterization studies we investigated the aerosol performance of TPIP in response to changes in capsule fil...

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Autors principals:	Helena Gauani, Thomas Baker, Zhili Li, Vladimir S. Malinin, Walter Perkins, Eugene Sullivan, David Cipolla
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2022-04-01
Col·lecció:	Frontiers in Drug Delivery
Matèries:	device performance dry powder inhaler drug delivery aerosol characterization treprostinil palmitil fine particle dose
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fddev.2022.864922/full
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