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Mitochondrial DNA copy number in patients with systemic sclerosis

Introduction: Systemic scleroderma (SSc) is a chronic autoimmune disease of inflammatory origin. Mitochondrial dysfunction is considered as an important mechanism in the pathogenesis of SSc. Currently mitochondrial DNA (mtDNA) copy number is used as a surrogate marker of mitochondrial dysfunction. P...

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Principais autores: Anastasia I. Bogatyreva, Elena V. Gerasimova, Tatiana V. Kirichenko, Yuliya V. Markina, Taisiya V. Tolstik, Diana G. Kiseleva, Tatiana V. Popkova, Alexander M. Markin
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-12-01
Serier:Frontiers in Molecular Biosciences
Fag:
DNA
mitochondrial
monocytes
systemic sclerosis
autoimmunity
inflammation
Online adgang:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1313426/full
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