N6‐methyladenosine demethylase ALKBH5 suppresses colorectal cancer progression potentially by decreasing PHF20 mRNA methylation

Abstract Background As the most widespread mRNAs modification, N6‐methyladenosine (m6A) is dynamically and reversibly modulated by methyltransferases and demethylases. ALKBH5 is a major demethylase, and plays vital roles in the progression of cancers. However, the role and mechanisms of ALKBH5 in co...

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Detalhes bibliográficos

Principais autores:	Zhen Zhang, Ling Wang, Long Zhao, Quan Wang, Changjiang Yang, Mengmeng Zhang, Bo Wang, Kewei Jiang, Yingjiang Ye, Shan Wang, Zhanlong Shen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2022-08-01
coleção:	Clinical and Translational Medicine
Assuntos:	ALKBH5 colorectal cancer m6A modification PHF20
Acesso em linha:	https://doi.org/10.1002/ctm2.940
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