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Structure of the ALS Mutation Target Annexin A11 Reveals a Stabilising N-Terminal Segment

The functions of the annexin family of proteins involve binding to Ca<sup>2+</sup>, lipid membranes, other proteins, and RNA, and the annexins share a common folded core structure at the C terminus. Annexin A11 (AnxA11) has a long N-terminal region, which is predicted to be disordered, binds RNA, an...

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Kaydedildi:
Asıl Yazarlar: Peder A. G. Lillebostad, Arne Raasakka, Silje J. Hjellbrekke, Sudarshan Patil, Trude Røstbø, Hanne Hollås, Siri A. Sakya, Peter D. Szigetvari, Anni Vedeler, Petri Kursula
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI AG 2020-04-01
Seri Bilgileri:Biomolecules
Konular:
annexin A11
crystal structure
solution structure
calcium binding
membrane binding
protein stability
Online Erişim:https://www.mdpi.com/2218-273X/10/4/660
Etiketler: Etiketle
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