The transcription factor Stat-1 is essential for Schwann cell differentiation, myelination and myelin sheath regeneration

Abstract Background Myelin sheath is a crucial accessory to the functional nerve-fiber unit, its disruption or loss can lead to axonal degeneration and subsequent neurodegenerative diseases (NDs). Notwithstanding of substantial progress in possible molecular mechanisms underlying myelination, there...

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Detalhes bibliográficos

Principais autores:	Jinghui Xu, Bin Zhang, Jieyi Cai, Qianqian Peng, Junxia Hu, Parizat Askar, Jianghong Shangguan, Wenfeng Su, Changlai Zhu, Hualin Sun, Songlin Zhou, Gang Chen, Xiaoming Yang, Yun Gu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-06-01
coleção:	Molecular Medicine
Assuntos:	Stat1 Schwann cells Differentiation Myelination and remyelination Demyelinating diseases
Acesso em linha:	https://doi.org/10.1186/s10020-023-00667-w
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