Côd QR

cFOS-SOX9 Axis Reprograms Bone Marrow-Derived Mesenchymal Stem Cells into Chondroblastic Osteosarcoma

Bone marrow-derived mesenchymal stem cells (BMSCs) are proposed as the cells of origin of several subtypes of osteosarcoma (OS). However, signals that direct BMSCs to form different subtypes of OS are unclear. Here we show that the default tumor type from spontaneously transformed p53 knockout (p53_...

Disgrifiad llawn

Wedi'i Gadw mewn:
Prif Awduron: Yunlong He, Wentao Zhu, Min Hwa Shin, Joy Gary, Chengyu Liu, Wendy Dubois, Shelley B. Hoover, Shunlin Jiang, Eryney Marrogi, Beverly Mock, R. Mark Simpson, Jing Huang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2017-06-01
Cyfres:Stem Cell Reports
Pynciau:
mesenchymal stem cells
p53
osteosarcoma
cFOS
SOX9
RAS
AKT
stem cells
cancer
cancer stem cells
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S2213671117301832
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg