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Selection acts on DNA secondary structures to decrease transcriptional mutagenesis.

Single-stranded DNA is more subject to mutation than double stranded. During transcription, DNA is transiently single stranded and therefore subject to higher mutagenesis. However, if local intra-strand secondary structures are formed, some bases will be paired and therefore less sensitive to mutati...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Claire Hoede, Erick Denamur, Olivier Tenaillon
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science (PLoS) 2006-11-01
Sarja:PLoS Genetics
Linkit:http://europepmc.org/articles/PMC1630709?pdf=render
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