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Multiple Molecular Mechanisms Rescue mtDNA Disease in C. elegans

Summary: Genetic instability of the mitochondrial genome (mtDNA) plays an important role in human aging and disease. Thus far, it has proven difficult to develop successful treatment strategies for diseases that are caused by mtDNA instability. To address this issue, we developed a model of mtDNA di...

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Váldodahkkit: Suraiya Haroon, Annie Li, Jaye L. Weinert, Clark Fritsch, Nolan G. Ericson, Jasmine Alexander-Floyd, Bart P. Braeckman, Cole M. Haynes, Jason H. Bielas, Tali Gidalevitz, Marc Vermulst
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Elsevier 2018-03-01
Ráidu:Cell Reports
Liŋkkat:http://www.sciencedirect.com/science/article/pii/S2211124718303097
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