Specific death of ALT cells through TSPYL5 depletion
Some tumors acquire replicative immortality by activating an ALTernative telomerase-independent telomere maintenance mechanism. ALT offers interesting therapeutic perspectives but lacks any known specific targets. We discovered a crucial role for TSPYL5 (Testis-Specific Y-encoded-Like Protein 5) in...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis Group
2019-11-01
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| Collection: | Molecular & Cellular Oncology |
| Sujets: | |
| Accès en ligne: | http://dx.doi.org/10.1080/23723556.2019.1651603 |
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