Specific death of ALT cells through TSPYL5 depletion
Some tumors acquire replicative immortality by activating an ALTernative telomerase-independent telomere maintenance mechanism. ALT offers interesting therapeutic perspectives but lacks any known specific targets. We discovered a crucial role for TSPYL5 (Testis-Specific Y-encoded-Like Protein 5) in...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis Group
2019-11-01
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| Edice: | Molecular & Cellular Oncology |
| Témata: | |
| On-line přístup: | http://dx.doi.org/10.1080/23723556.2019.1651603 |
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