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Dynamic immune status analysis of peripheral blood mononuclear cells in patients with Klebsiella pneumoniae bloodstream infection sepsis using single-cell RNA sequencing

BackgroundKlebsiella pneumoniae is a common Gram-negative bacterium. Blood infection caused by K. pneumoniae is one of the most common causes of human sepsis, which seriously threatens the life of patients. The immune status of peripheral blood mononuclear cells (PBMCs) based on single-cell RNA sequ...

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Guardat en:
Autors principals: Shengwei Zhang, Nan Zhang, Jing Han, Zeyu Sun, Hua Jiang, Wenhua Huang, Decong Kong, Qian Li, Yuhao Ren, Shishun Zhao, Yongqiang Jiang, Peng Liu
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2024-06-01
Col·lecció:Frontiers in Immunology
Matèries:
Klebsiella pneumoniae
sepsis
bloodstream
PBMCs
scRNA-seq
immune state
Accés en línia:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1380211/full
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