Single cell analysis identified IFN signaling activation contributes to the pathogenesis of pediatric steroid-sensitive nephrotic syndrome

Abstract Background Idiopathic nephrotic syndrome (INS) is a prevalent condition whose recurrence leads to multiple adverse effects. Previous studies on INS pathogenesis primarily focused on immune dysregulation, particularly T-cell changes and their correlation with cytokine shifts. Accumulating ev...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Qiu-Yu Li, Fei Liu, Xiaoyi Li, Minchao Kang, Linnan Bai, Tong Tong, Chen Zheng, Yanyan Jin, Xiaojing Zhang, Yi Xie, Dandan Tian, Yuanqing Pan, Jingjing Wang, Haidong Fu, Na Jiao, Junnan Wu, JianHua Mao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-05-01
coleção:	Biomarker Research
Assuntos:	Idiopathic nephrotic syndrome scRNA-seq IFN PBMCs
Acesso em linha:	https://doi.org/10.1186/s40364-025-00790-2
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!